Regulating insulin resistance is better than using insulin injections for type II because insulin produces hyperinsulinemia which is not good for people. It is my contention that using benfotiamine to lower insulin resistance stops the side effects of hyperinsulinemia. Thiamine loss can be caused by several circumstances. Having a diet heavy in processed cereals and white rice causes the body to eject thiamine when it is needed for heart output. Thiamine deficiency symptoms include weakened heart muscle and even heart failure. Read more.